–Ranikhet
DiseaseVaccine (K)
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Description : The vaccine is a
suspension of modified living virus (Ranikhet
(New Castle) Disease K. Strain) prepared
from the experimentally infected chicken
embryos and is freeze dried. The vaccine is
supplied with diluent. |
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Dose
and
Route of injection : The dose is 0.5 ml
to be inoculated subcutaneously or
intramuscularly. Optimum age of vaccination
is 6 to 8 weeks. It should be performed in
healthy flock only. if done perfectly the
resulting immunity is for its productive
life.
Reactions : After vaccination birds may
show some drowsiness, from the 3rd to the
6th day.1 to 3 % may become severely lame or
even paralyzed( usually seen in chicks not
protected with F1). birds showing slight
lameness or paralysis usually recover within
10 to 14 days. ordinarily a 2 % causality
may be expected.
Birds exhibiting illness or paralysis at a
later stage (after 2 to 3 weeks should be
suspected for Coccidiosis etc. vaccination
when done in laying hens the egg production
declines initially , but returns to normal
in 14 days. it is advisable to deworm the
birds against round worms of poultry one
week prior to this vaccination.
Preservation and shelf life : The
vaccine can be stored for one month in the
refrigeration temperature when transported
in ice, 3 months in the deep freezer and for
10 days at room temperature from the date of
issue.
Use
: The content of one vial should be
dissolved in 100 ml diluent . the
reconstituted vaccine should be kept cool
(in ice) and well protected from direct
sunlight and heat. it should be used within
2 hours after reconstitution.
Precautions:
It is not advisable to carry out
vaccination when there is outbreak of
Ranikhet disease., owing to the risk of
infecting the unaffected birds by the
operator. it is also contraindicated in a
flock affected with Coccidiosis or worms. If
done severe reaction and mortality may
occur.
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Fowl
Pox Vaccine
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Description :
Fowl – Pox Vaccine is a suspension of a
modified living virus ( ) prepared from the Chorio-allantoic membrane of the infected
embryo and is freeze dried. The vaccine is
supplied with diluent |
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use :
The
vaccine is used for protection of poultry
against fowl pox. each vial is sufficient
for vaccination of 100 birds above six weeks
of age.
Dose : The
content of each vial is diluted in 1 ml of
50 % glycerol saline solution to obtain a
homogenized suspension. the homogenized
suspension is kept in ice during the course
of its use. the reconstituted vaccine should
be used within three hours.
Vaccination :
Use a medium sized needle whose tip below
the eye is broken and rubbed smooth. Dip the
sterile needle in the vaccine, the
vaccination is done by wing web puncture.
Give two pricks at 1 cm apart, after dipping
in vaccine before pricking avoiding the
veins.
Preservation and
shelf life : It keeps well for 3 months in
the deep freezer at -15 to -20 o
c and 1 month in the refrigeration
temperature. If sent by post the vaccine
must be used within 10 days
Precautions :
The vaccine should not be used for
debilitated or worm infected birds or when
there is an outbreak of the same disease.
Unvaccinated chicken below 6 weeks of age
should not be allowed to come in contact
with vaccinated ones. The vaccinated birds
should be examined for takes seven days
after vaccination. If there is any
generalization of pox infection strict
segregation of birds should be carried out.
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Haemorrhagic Septicaemia (Broth)
Description :
The vaccine is a killed suspension of
Pasteurella multocida – P 52 strain in
nutrient broth with formaldehyde
Dose :
5 - 10 ml according to the size of animals
Route of injection : Subcutanious
Immunity : immunity is only for 2 - 3 months
Preservation and shelf life : stored at
refrigeration temperature , it retain
potency for 6 months.at room temperature it
can be stored for about 2 months.
Package :300 ml bottles.
Precautions : Animal should not be let out
for grazing for 7 days.
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Duck
Plague Vaccine
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Description
:
This vaccine is a modified living
virus prepared from the Chorio-allantoic
fluid, membrane and embryo of infected
chicken embryo and is freeze dried. The
vaccine is supplied with diluent.
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Dose : one
ampoule contain 200 doses. One ampoule is
diluted in 100 ml diluent and 0.5 ml is
given subcutaneously
Immunity : one
year
Preservation and
shelf life : In deep freezers it retains
potency for 10 to 12 months and in the
freezing chamber of refrigerator for 1
month. Transportaion must be under
refrigeration.
Schedule of
Vaccination: In healthy atmosphere first
vaccination is given at the 7th week and a
booster dose is given in the 4th month.(
immunity develops in one week and last for
an year.) in the face of an outbreak first
vaccination can be done from the 3rd week of
age followed by a second vaccination after 4
weeks and booster after 4 months.
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Haemorrhagic
Septicaemia (OA)
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Description
: The vaccine is a homogenous
suspension of formalinised agar washed
Pasteurella multocida P 52 strain in
liquid paraffin and lanolin.
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Dose : 2 ml intramuscularly for animals
weighing less than 140 kg. 3ml for
animals weighing above 140 kg.
Route of
injection : The vaccine is to be given
intramuscularly and the site of
inoculation should be given a gentle
massage.
Reactions :
A slight swelling may develop at the
site of inoculation which may persist
for some time.
Immunity :
The immunity following vaccination is
established after 21 days and lasts for
about one year.
Preservation
and shelf life : Under refrigeration
temperature it keeps well for about one
year. At room temperature it can be
stored for about 2 months.
Package :
Bottles of 100 ml
Precautions : The vaccine bottle
should be thoroughly shaken before use.
Animals should not be sent for grazing
for 7 days following vaccination. The
vaccine should not be used during an
outbreak. Strict aseptic precaution must
be observed during vaccination lest it
may develop into an abscess.
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Black
Quarter Vaccine (I.P)
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Description : The vaccine is a culture
of clostridium chauvoei grown in
anaerobic fluid medium, rendered sterile
and atoxic by the addition of
formaldehyde solution in such a manner
that it retains its immunizing
properties |
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Dose : The
vaccine is inoculated subcutaneously.
Cattle 5 - 10 ml, sheep & goat 2 - 3 ml.
a second vaccination at the same dosage
rate may be carried out ten days after
the first inoculation in cases where a
high degree of immunity is considered
essential.
Reactions :
A slight swelling at the site of
inoculation may result and persist for 2
- 3 days.
Immunity :
The immunity becomes fully established
in a fortnight after vaccination and
persist for about a year.
Preservation
and shelf life :The vaccine should be
stored in the refrigerator or cold room
at a temperature of 2- 5 0 c. it keeps
well for 6 months at this temperature.
if sent by parcel the vaccine must be
used within a month.
Package
:300 ml bottles.
Precautions
: The vaccine
should not be used during an outbreak.
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Duck
Pasteurella Vaccine
This vaccine is
a homogenous suspension of formalinised agar
washed Pasteurella multocida (Niranam
strain) in liquid paraffin and lanolin. The
vaccine will be released soon.
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Brucella abortus S 19 vaccine (live, freeze
dried)
This new vaccine for the
bovine brucellosis has been developed and
standardized in our laboratory. this vaccine
is for the use in female calves of the age
above 4 months. It will made available for
the end of 2004 after necessary approval for
the national control authority.
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Rabies
vaccine. Vet, Inactivated, (cell
culture)
The institute is planning
to produce cell culture rabies vaccine from
2004. For this a detailed project for 15
million RS has been submitted to the
government. A new facility will be
constructed this year meeting the WHO GMP
requirement. The vaccine will be produced in
BHK 21 cell culture. the technical Know-how
for this vaccine was received from the
Pasteur Institute of India, Coonoor. The
production is expected from the beginning of
2005.( for details contact)
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Combined HS- BQ vaccine |
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A new formulation for
the HS and BQ was developed in our
research and development laboratory
and has passed initial evaluation .
this new combination is now under
field trials. |
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Viral Vaccines
